Effect of Shenqiwan on Learning and Memory Abilities and Superoxidation of Brain Tissue in Senile Rats

To observe the effect of Shenqiwan on learning and memory functions in senile model mice induced by D-galactose,40 Wistar rats were dividied into control group,model group,treating group 1(low dosage),treating group2(high dosage).The aging models were induced with D-galactose.The memory function was tested with passage way water maze.The activity of superoxide dismutase(SOD),content of malodialdehyde(MDA)and glutathione peroxidase(GSH-PX) were measured.After sixty days treating with Shenqiwan,the swimming time significantly shortened and the correct number increased significantly in Shenqiwan groups compared with the model group.The activities of SOD and GSH-PX increased and the content of MDA decreased in Shenqiwan groups compared with that in the model group.Shenqiwan can improve the learning and memory functions in aging rats induced with D-glalactose and resist lipid peroxidation in brain tissue.