Analysis of urine protein and plasma-albumin levelin primary nephrotic syndromewith sequential therapy by regular dose methylprednisolone and prednisone

Objective To analyze theefficacyof urine protein and plasma-albumin withregular dose methylprednisolone,prednisone of sequential therapy in primary nephrotic syndrome.Methods 80patients with primary nephrotic syndrome were divided into two groups according to pathological type,glucocorticoids group(A),and another group(B)with glucocorticoid and cytotoxic drugs.Then each groupwas randomly divided into two groups,namely,the application of methylprednisolone group(treatment group)and oral prednisone group(control group),and made an curative effect analysis.Results The effect of the 24hour urinary protein excretion,plasma albumin,cholesterol in treatment groupwas superior to those in the control group,There was no significantstatistical difference(P0.05).Conclusion The treatment of the regular dose of methylprednisolone,prednisone sequential therapy can more quickly relieve the urine protein and increase plasma-albuminthan regular prednisone application in primary nephrotic syndrome.