Analysis on the change of complete blood cell parameters and blood coagulation indices in parturient pregnant women

Objective To investigate the change of complete blood cell parameters and blood coagulation indices in parturient pregnant women and its clinical significance.Methods 530 cases of parturient pregnant women (parturient group) and 140 cases of non-pregnant women (control group) were detected for blood cell parameters and blood coagulation indices with Sysmex K-4500 blood cell analyzer and STA-R automatic blood coagulation analyzer.Results White blood cell count (WBC), granulocyte percentage (GRA%), red blood cell volume distribution width (RDW), platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), platelet large cell ratio (P-LCR%) and fibrinogen (Fib) were significantly higher (P0.05 or P0.01); lymphocyte percentage (LYM%), mid cell ratio (MID%), red blood cell count (RBC), hemoglobin (Hb), hematocrit (HCT), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), prothrombin time (PT), prothrombin time-international normalized ratio (PT-INR), and activated partial thromboplasting time (APTT) were significantly lower (P0.01) in parturient group than those of control group. There were no statistical differences of mean corpuscular volume (MCV) and thrombin time (TT) between parturient group and control group (P0.05).Conclusion Different degree of iron deficiency anemia and hypercoagulabale state occur in parturient pregnant women, which is liable to disseminated intravascular coagulation (DIC).