2012•Medical Journal of Chinese People's HealthRequires access

The clinical research of Aripiprazole combined with Clozapine in refractory schizophrenia

Shen Ping

Abstract

Objective:To study the aripiprazole combined with clozapine for the for the treatment in refractory schizophrenia therapeutic efficacy and side effect respectively.Methods:45 patients of clozapine in refractory schizophrenia combined with aripiprazole,PANSS and TESS were used to assess the therapeutic efficacy and side effect respectively before treatment、after treatment with 2、 4、 8、12 weekend.Results: The patients combined with aripiprazole PANSS scores decreased significantly(P0.05),the total side effect respectively decreased significantly(P0.05).Conclusions: Aripiprazole combined with clozapine in the treatment of refractory schizophrenia has good therapeutic efficacy,high safety,can be used as a good choice.

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Key concepts: Aripiprazole, Clozapine, Schizophrenia (object-oriented programming), Refractory (planetary science), Medicine, Therapeutic effect, Side effect (computer science), Internal medicine