The Clinical Analysis of 138 Cases With CIN

Objective To explore the best policy for clinical treatment of CIN,and evaluate the therapeutic efficacy of conization of cervix for CIN.Methods For 138 cases with CIN who had received follow-up visit and HPV-DNA test, conization,hysterectomy or radical hysterectomy from 2008 to 2010 year,we retrospectively analyzed the therapeutic efficacy of follow-up visit termination,the different pathologic diagnosis after conization,the recurrence after conization 1 year later. Results 138 cases with CIN were diagnosed by biopsy.47 cases of CINⅠreceived follow-up visit and HPV-DNA test.After 1 year follow-up visit,28 cases were negative,5 cases with HPV-DNA had higher grade pathology,14 cases maintain CIN I;49 cases of CINⅡand 42 cases of CINⅢreceived conization,among the 91 cases of CINⅡ/Ⅲafter conization,surgical pathology was negative in 4 cases,15 had higher grade pathology than biopsy in 91 cases,59 cases' pathology maintain unchanging perioperatively.There were 14 cases received hysterectomy after conization,1 case received radical hysterectomy.There were 2 recurrent cases in 76 cases with CIN who were treated by conization 1 year later. Conclusions The incidence of CIN tends to increase and the patients become younger and younger.The LEEP conization of cervix is of great value in the treatment of CINⅡ/Ⅲ,follow-up visit is the first policy for CINⅠ.