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Flavonoid glycosides in Potentilla multicaulis Bunge

Wu Wen

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Abstract

Objective To determine the chemical constituents in Potentilla multicaulis Bunge.Methods The plants were extracted with 70% ethanol,and the ethanol extract was submitted to chromatography on macroporous resin,silica gel column,ODS and Sephadex LH-20 gel chromatography,to isolate some compounds.Their structures were established by chemical and spectral methods.Results Five flavonoid glycosides and one essential oil were isolated and identified as: potengriffioside A(Ⅰ),quercetin-3-O-α-L-rhamnoside(Ⅱ),quercetin-3-O-β-D-glucoside(Ⅲ),kaempferol-3-O-β-D-glucoside(Ⅳ),isorhamnetin-3-O-β-D-glucopyranosyl-7-O-α-L-rhamnopyranoside(Ⅴ),and di(2-ethylhexyl)phthalate(Ⅵ).Conclusion CompoundsⅠ-Ⅳ,Ⅵ are obtained from Potentilla multicaulis Bunge and compound Ⅴ is purified from Potentilla Genus for the first time.

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Objective To determine the chemical constituents in Potentilla multicaulis Bunge.Methods The plants were extracted with 70% ethanol,and the ethanol extract was submitted to chromatography on macroporous resin,silica gel column,ODS and Sephadex LH-20 gel chromatography,to isolate some compounds.Their structures were established by chemical and spectral methods.Results Five flavonoid glycosides and one essential oil were isolated and identified as: potengriffioside A(Ⅰ),quercetin-3-O-α-L-rhamnoside(Ⅱ),quercetin-3-O-β-D-glucoside(Ⅲ),kaempferol-3-O-β-D-glucoside(Ⅳ),isorhamnetin-3-O-β-D-glucopyranosyl-7-O-α-L-rhamnopyranoside(Ⅴ),and di(2-ethylhexyl)phthalate(Ⅵ).Conclusion CompoundsⅠ-Ⅳ,Ⅵ are obtained from Potentilla multicaulis Bunge and compound Ⅴ is purified from Potentilla Genus for the first time.

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Available abstract

Objective To determine the chemical constituents in Potentilla multicaulis Bunge.Methods The plants were extracted with 70% ethanol,and the ethanol extract was submitted to chromatography on macroporous resin,silica gel column,ODS and Sephadex LH-20 gel chromatography,to isolate some compounds.Their structures were established by chemical and spectral methods.Results Five flavonoid glycosides and one essential oil were isolated and identified as: potengriffioside A(Ⅰ),quercetin-3-O-α-L-rhamnoside(Ⅱ),quercetin-3-O-β-D-glucoside(Ⅲ),kaempferol-3-O-β-D-glucoside(Ⅳ),isorhamnetin-3-O-β-D-glucopyranosyl-7-O-α-L-rhamnopyranoside(Ⅴ),and di(2-ethylhexyl)phthalate(Ⅵ).Conclusion CompoundsⅠ-Ⅳ,Ⅵ are obtained from Potentilla multicaulis Bunge and compound Ⅴ is purified from Potentilla Genus for the first time.

Key concepts: Potentilla, Chemistry, Glycoside, Isorhamnetin, Silica gel, Column chromatography, Chromatography, Sephadex

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