Biochemical Index Changes in Cerebral Infarction Patients with Different Degrees of Carotid Artery Stenosis

Objective To observe biochemical changes in cerebral infarction patients with different degrees of carotid artery stenosis,and supply experimental basis for the development and progression of carotid artery stenosis.Methods Clinical data of 100 patients of cerebral infarction with carotid artery stenosis were retrospectively analyzed,which were divided into three groups by ultrasound Doppler flow imaging features.Group 1:34 patients,degree of carotid artery stenosis was normal or less than 50%;group 2:33 patients,degree of carotid artery stenosis was 50% to 69%;group 3:23 patients,degree of carotid artery stenosis was 70% to total occlusion.Control group:50 healthy people who received physical examination in the hospital during the period.Each group was measured by serum homocysteine(HCY),total cholesterol(TC),triglyceride(TG)and glucose(GLU),results were compared with each other.Results Cerebral infarction HCY,TC,TG and GLU levels were higher,the difference was statistically significant(P0.05).HCY,TC,TG,GLU levels increased along with unilateral carotid stenosis increase,the difference among the three groups was significant(P0.05);TC,TG also increased with the bilateral side of the carotid stenosis increase,but the difference among the three groups was not significant(P0.05),Serum GLU and HCY levels increased,and the difference between the three groups was statistically significant(P0.05).Conclusion HCY,TC,TG and GLU are major risk factors in the occurrence and development of carotid artery stenosis.