2011Journal of Henan University of Science & TechnologyRequires access

Clinical Value of Tumor Marker Allied Detection in Diagnosis of Lung Cancer

Chun-hua Yu, Tan Shanjuan, Yongjun Wu

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Abstract

Objective To study the clinical value of the combined detection of tumor markers in the diagnosis of lung cancer. Methods The clinical data and serum levels of CA19-9,CEA,NSE and CA125 of 30 patients with lung cancer and 30 patients with benign lung disease were retrospectively reviewed from June,2010 to Nov.2010. Results The levels of serum CA19-9,NSE and CA125 in lung cancer group were significantly different from benign lung diseases group(P0.05).The sensitivity,specificity and accuracy of four tumor markers were 70%,93.33% and 81.67%,respectively. Conclusion The combined detections of CA19-9,CEA,NSE and CA125 are very useful for the diagnostic value of lung cancer patients which will provide a scientific and reliable evidence for differentiating lung cancer from benign lung disease.

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What this paper is about

Objective To study the clinical value of the combined detection of tumor markers in the diagnosis of lung cancer. Methods The clinical data and serum levels of CA19-9,CEA,NSE and CA125 of 30 patients with lung cancer and 30 patients with benign lung disease were retrospectively reviewed from June,2010 to Nov.2010. Results The levels of serum CA19-9,NSE and CA125 in lung cancer group were significantly different from benign lung diseases group(P0.05).The sensitivity,specificity and accuracy of four tumor markers were 70%,93.33% and 81.67%,respectively. Conclusion The combined detections of CA19-9,CEA,NSE and CA125 are very useful for the diagnostic value of lung cancer patients which will provide a scientific and reliable evidence for differentiating lung cancer from benign lung disease.

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Available abstract

Objective To study the clinical value of the combined detection of tumor markers in the diagnosis of lung cancer. Methods The clinical data and serum levels of CA19-9,CEA,NSE and CA125 of 30 patients with lung cancer and 30 patients with benign lung disease were retrospectively reviewed from June,2010 to Nov.2010. Results The levels of serum CA19-9,NSE and CA125 in lung cancer group were significantly different from benign lung diseases group(P0.05).The sensitivity,specificity and accuracy of four tumor markers were 70%,93.33% and 81.67%,respectively. Conclusion The combined detections of CA19-9,CEA,NSE and CA125 are very useful for the diagnostic value of lung cancer patients which will provide a scientific and reliable evidence for differentiating lung cancer from benign lung disease.

Key concepts: Lung cancer, Medicine, Tumor marker, Internal medicine, Lung, Cancer, Pathology, Oncology

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