2015•The Journal of Medical Theory and PracticeRequires access
Effects of Rosuvastatin with Different Doses of Statins Atorvastatin on Inflammatory Factors in Patients with Acute Coronary Syndrome
Wang Ai-qi
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Abstract
Objective:To investigate the effects of different dose of atorvastatin and rosuvastatin treatment comprehensive clinical effect in patients with acute coronary syndrome.Methods:According to the different treatment 135 cases of acute coronary syndrome patients were grouped,rosuvastatin group 45cases(10mg rosuvastatin),atorvastatin group A 45cases(10mg atorvastatin)and atorvastatin group B 45cases(20mg atorvastatin),the changes of blood lipid the inflammatory factor and compared before and after treatment in three groups.Results:Rosuvastatin,atorvastatin group B in patients with PAI-1,MMP-9,TC,LDL-C decreased significantly better than atorvastatin group A,P0.05;rosuvastatin no significant correlation between the changes of serum levels of inflammatory factors in the atorvastatin group and blood lipid level.Conclusion:The use of rosuvastatin and atorvastatin treatment ACS can effectively make inflammation factors level in serum decreased,and the decreased effect of drug related with measurement.