Experimental study of arteritis and thrombus caused by keeping peripheral artery catheter

Objective To study the correlation of pathologic change in blood vessel caused by I.A catheter in peripheral artery and indwelling time,in order to confirm safe indwelling time and reduce the injury of blood vessel.Methods Health New Zealand rabbits with the same kind and weight were divided into two groups randomly,the first group with eight and the second with nine rabbits.The arteries on the backside of the two ears were taken as tested blood tubes for I.A catheter and the catheters were retained for 96h and 168h.2cm long and 1cm width samples with artery and ear structure upstream the puncture point were taken as pathological section for the observation of artery pathologic change.(Results Inflammation) rate of the two groups is respectively 46.67% and 94.44%,P0.005,the difference was significant in statistics.The thrombus rates of the two groups were respectively 40% and 55.56%.P0.05,the difference is significant.Conclusions Indwelling time of I.A.catheter and the inflammation rate around indwelling artery were in positive correlation.