Evaluation of right ventricular function by tissue Doppler-derived Tei index in children with congenital heart disease

Objective:To explore the value of right ventricular function evaluation in tissue Doppler-derived Tei index(TDI-Tei) in children with congenital heart disease(CHD).Methods:The right ventricular Tei indexes(TDI-Tei index and PWD-Tei index) of 46 CHD children(divided into pulmonary hypertension group and non-pulmonary hypertension group according to their pulmonary arterial systolic pressure) and 33 healthy children were measured by tissue Doppler method and Doppler flow imaging method and compared.Results:①The right ventricular PWD-Tei index in non-pulmonary hypertension group was higher than that in control group(0.32±0.05 vs 0.30±0.04),without significant difference(P0.05);the right ventricular DTI-Tei index in non-pulmonary hypertension group was higher than that in control group(0.34±0.06 vs 0.31±0.04)(P0.05).The right ventricular PWD-Tei index and DTI-Tei index in pulmonary hypertension group were higher than those in non-pulmonary hypertension group(0.51±0.11 vs 0.32±0.05,P0.001;0.55±0.12 vs 0.34±0.06,P0.001).②There was correlation between right ventricular PWD-Tei index and DTI-Tei index in each group.③Compared with right ventricular PWD-Tei index(γ=0.79,P0.001),a better correlation was observed between right ventricular TDI-Tei index and pulmonary arterial systolic pressure(γ=0.86,P0.001).For evaluating pulmonary hypertension of CHD children,the sensitivity and specificity of DTI-Tei index were higher than those of PWD-Tei index(sensitivity: 78% vs 71%;specificity:90% vs 87%).Conclusion:Tissue Doppler-derived Tei index can reflect the changes of right ventricular function of CHD children sensitively,which is a useful index for evaluating total function of right ventricle and indicative index of CHD children combined with pulmonary hypertension or not.