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Analysis on detection of serum myocardial enzymes in children with hand,foot and mouth disease

Chen Yue-song

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Abstract

Objective To study the changes of serum myocardial enzymes in the children with hand,foot and mouth disease(HFMD) and to explore its clinical significance.Methods Fasting serum myocardial enzymes,excluding aspartate aminotransferase(AST),lactate dehydrogenase(LDH),creatine kinase(CK) and creatine kinase isoenzyme(CK-MB) were examined in 187 cases with HFMD on the next day of diagnosis and the end of course of disease.Results The children with HFMD had higher myocardial enzymes compared with the control group(P0.01).The abnormality of myocardial enzymes before treatment was significantly higher than that after treatment(P0.01),but no myocarditis manifestation occurred.Conclusion Myocardium is easy to be damaged in the course of HFMD,which has good prognosis after the treatment.

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What this paper is about

Objective To study the changes of serum myocardial enzymes in the children with hand,foot and mouth disease(HFMD) and to explore its clinical significance.Methods Fasting serum myocardial enzymes,excluding aspartate aminotransferase(AST),lactate dehydrogenase(LDH),creatine kinase(CK) and creatine kinase isoenzyme(CK-MB) were examined in 187 cases with HFMD on the next day of diagnosis and the end of course of disease.Results The children with HFMD had higher myocardial enzymes compared with the control group(P0.01).The abnormality of myocardial enzymes before treatment was significantly higher than that after treatment(P0.01),but no myocarditis manifestation occurred.Conclusion Myocardium is easy to be damaged in the course of HFMD,which has good prognosis after the treatment.

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Available abstract

Objective To study the changes of serum myocardial enzymes in the children with hand,foot and mouth disease(HFMD) and to explore its clinical significance.Methods Fasting serum myocardial enzymes,excluding aspartate aminotransferase(AST),lactate dehydrogenase(LDH),creatine kinase(CK) and creatine kinase isoenzyme(CK-MB) were examined in 187 cases with HFMD on the next day of diagnosis and the end of course of disease.Results The children with HFMD had higher myocardial enzymes compared with the control group(P0.01).The abnormality of myocardial enzymes before treatment was significantly higher than that after treatment(P0.01),but no myocarditis manifestation occurred.Conclusion Myocardium is easy to be damaged in the course of HFMD,which has good prognosis after the treatment.

Key concepts: Hand-foot-and-mouth disease, Creatine kinase, Medicine, Lactate dehydrogenase, Myocarditis, Enzyme, Internal medicine, Disease

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Analysis on detection of serum myocardial enzymes in children with hand,foot and mouth disease — Research Paper | ScholarLens