Change and significance of D-dimer,FIB in plasma in acute phase of hypertensive cerebral hemorrhage

Objective To investigate the dynamic change and clinical significance of plasma D-dimer, FIB levels of the patients with acute phase of hypertensive cerebral hemorrhage. Methods To detect the plasma D-dimer, FIB levels of the patients with hypertensive cerebral hemorrhage by magnetism pearls, and to compare with 40 healthy persons. Results The levels of D-dimer, FIB in plasma of the patients with hypertensive cerebral hemorrhage were higher on day 1, 3 and day 3, 7 respectively than those of in controls(P0.05). The groups of bad prognosis had significantly higher levels of D-dimer than those of good prognosis(P0.01). The patients of bad prognosis were almost sufferers that haematomata crashed through cerebral ventricle or subarachnoid cavity. Conclusion The plasma D-dimer levels of the patients with hypertensive cerebral hemorrhage are significantly high, indicating the possibility that the activation of fibrinolysis is inclined to increase in forepart. The plasma D-dimer levels of the patients with hypertensive cerebral hemorrhage correlate with the position of hemorrhage and prognosis.