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Focal nodular hyperplasia of the liver:the value of MRI and CT diagnosis

Haodan Dang

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Abstract

Objective:To investigate the value of MR imaging in diagnosis of focal nodular hyperplasia(FNH) of the liver.Methods:19 cases with FNH(total 21 lesions) proved pathologically examined by CT and MRI.Non-contrast enhanced and dynamic contrast enhanced scanning were performed on 19 patients.Cell specific contrast-enhanced scanning was performed on 3 cases.The finding of CT and MRI of FNH were analysed and compared.Results:Of 21 FNH on non-enhanced scanning,17 FNH manifested isointensity or lightly hypointensity on T1WI and lightly hyperintensity on T2WI.12 central scars and 3 thicken central vessel and 3 pseudocapsule of FNH were found on non-contrast enhanced MRI,more than on non-contrast enhanced CT.21 FNH had obvious enhancement during arterial phase,and 16 FNH signal intensity were becoming to near the liver during portal phase or delayed phase.The central scar and pseudocapsule were enhanced during late portal phase and delayed phase.On cell specific contrast-enhanced scanning,the parenchymal of FNH were markedly enhanced on 3 cases,whereas the central scar were not enhanced,becoming more clear.Conclusion:Most FNH having characteristic findings on MRI,can be correctly diagnosed.To FNH,the value of MRI diagnosis is higher than CT.

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Objective:To investigate the value of MR imaging in diagnosis of focal nodular hyperplasia(FNH) of the liver.Methods:19 cases with FNH(total 21 lesions) proved pathologically examined by CT and MRI.Non-contrast enhanced and dynamic contrast enhanced scanning were performed on 19 patients.Cell specific contrast-enhanced scanning was performed on 3 cases.The finding of CT and MRI of FNH were analysed and compared.Results:Of 21 FNH on non-enhanced scanning,17 FNH manifested isointensity or lightly hypointensity on T1WI and lightly hyperintensity on T2WI.12 central scars and 3 thicken central vessel and 3 pseudocapsule of FNH were found on non-contrast enhanced MRI,more than on non-contrast enhanced CT.21 FNH had obvious enhancement during arterial phase,and 16 FNH signal intensity were becoming to near the liver during portal phase or delayed phase.The central scar and pseudocapsule were enhanced during late portal phase and delayed phase.On cell specific contrast-enhanced scanning,the parenchymal of FNH were markedly enhanced on 3 cases,whereas the central scar were not enhanced,becoming more clear.Conclusion:Most FNH having characteristic findings on MRI,can be correctly diagnosed.To FNH,the value of MRI diagnosis is higher than CT.

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Available abstract

Objective:To investigate the value of MR imaging in diagnosis of focal nodular hyperplasia(FNH) of the liver.Methods:19 cases with FNH(total 21 lesions) proved pathologically examined by CT and MRI.Non-contrast enhanced and dynamic contrast enhanced scanning were performed on 19 patients.Cell specific contrast-enhanced scanning was performed on 3 cases.The finding of CT and MRI of FNH were analysed and compared.Results:Of 21 FNH on non-enhanced scanning,17 FNH manifested isointensity or lightly hypointensity on T1WI and lightly hyperintensity on T2WI.12 central scars and 3 thicken central vessel and 3 pseudocapsule of FNH were found on non-contrast enhanced MRI,more than on non-contrast enhanced CT.21 FNH had obvious enhancement during arterial phase,and 16 FNH signal intensity were becoming to near the liver during portal phase or delayed phase.The central scar and pseudocapsule were enhanced during late portal phase and delayed phase.On cell specific contrast-enhanced scanning,the parenchymal of FNH were markedly enhanced on 3 cases,whereas the central scar were not enhanced,becoming more clear.Conclusion:Most FNH having characteristic findings on MRI,can be correctly diagnosed.To FNH,the value of MRI diagnosis is higher than CT.

Key concepts: Focal nodular hyperplasia, Medicine, Radiology, Magnetic resonance imaging, Hyperintensity, Nuclear medicine, Contrast enhancement, Hepatocellular carcinoma

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