Application value of procalcitonin in condition assessment and prognosis judgment of sepsis

Objective To investigate application value of procalcitonin in condition assessment and prognosis judgment of sepsis. Methods 200 patients with severe sepsis admitted our hospital of intensive care unit from August 2009 to June 2014 were selected,including sepsis group of 140 cases,local infection group of 60 cases.According to the sepsis patient′s illness severity,the patients with sepsis were classified into shock group and non-shock group.According to the sepsis patient′s prognosis,the patients with sepsis were classified into survival group and death group.After the subject,APACHE Ⅱ score was applied.Serum PCT and the dynamic change of patients with sepsis infection were monitored,compared and analyzed. Results There was statistical difference on the level of first PCT between sepsis group and local infection group(P0.01).There were statistical difference on the level of first PCT,APACHEⅡ score between shock group and non-shock group(P0.01).The level of PCT in survival group decreased,the level of PCT in death group increased slowly,and maintain a higher level. Conclusion The level of serum PCT has a high sensitivity and specificity for early diagnosis,assessment of severity and prognosis of sepsis.The dynamic change of the PCT level can be used as basis of condition assessment,prognosis and adjust the treatment plan,which has a significant value in sepsis treatment process.