2007Pharmaceutical and Clinical ResearchRequires access

Coumarins from the pericarp of Citrus grandis

Wen‐Cai Ye

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Abstract

Objective:To study the chemical constituents of the pericarp of Citrus grandis.Methods: Compounds were isolated by several kinds of chromatographic methods.The structures were determined on the basis of spectral and chemical evidence.Results: Ten coumarins were isolated from the peels of Citrus grandis.The structures of these coumarins were identified as 8-(3-hydroxy-2-methoxy-3-methylbutyl)-7-methoxy coumarin(1),mexoticin(2),epoxyaurapten(3),isomeranzin(4),meranzin hydrate(5),isomeranzin(6),isoimperatorin(7),aurapten(8),osthol(9)and 7-hydroxycoumarin(10).Conclusion:Compounds 1~4 were isolated from this plant for the first time.

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What this paper is about

Objective:To study the chemical constituents of the pericarp of Citrus grandis.Methods: Compounds were isolated by several kinds of chromatographic methods.The structures were determined on the basis of spectral and chemical evidence.Results: Ten coumarins were isolated from the peels of Citrus grandis.The structures of these coumarins were identified as 8-(3-hydroxy-2-methoxy-3-methylbutyl)-7-methoxy coumarin(1),mexoticin(2),epoxyaurapten(3),isomeranzin(4),meranzin hydrate(5),isomeranzin(6),isoimperatorin(7),aurapten(8),osthol(9)and 7-hydroxycoumarin(10).Conclusion:Compounds 1~4 were isolated from this plant for the first time.

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Available abstract

Objective:To study the chemical constituents of the pericarp of Citrus grandis.Methods: Compounds were isolated by several kinds of chromatographic methods.The structures were determined on the basis of spectral and chemical evidence.Results: Ten coumarins were isolated from the peels of Citrus grandis.The structures of these coumarins were identified as 8-(3-hydroxy-2-methoxy-3-methylbutyl)-7-methoxy coumarin(1),mexoticin(2),epoxyaurapten(3),isomeranzin(4),meranzin hydrate(5),isomeranzin(6),isoimperatorin(7),aurapten(8),osthol(9)and 7-hydroxycoumarin(10).Conclusion:Compounds 1~4 were isolated from this plant for the first time.

Key concepts: Coumarin, Rutaceae, Chemistry, Chemical constituents, Hydrate, Spectral analysis, Chromatography, Botany

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