Clinical Research of Mongolian Medicine Aoqirinailega in Treatment of Rheumatoid Arthritis

Objective: To objective evaluate the clinical effect of Mongolian medicine Aoqirinailega in treatment of rheumatoid arthritis through clinical trials.Methods: 72 cases of rheumatoid arthritis were randomly divided into treatment group and control group.The treatment group were treated with methotrexate(MTX) + Mongolian medicine Aoqirinailega,the control group were treated with MTX,observing the symptoms and signs during treatment,detecting the hand anterioposterior films,routine blood test,liver function and kidney function before and after treatment.Results: ① The effective rate of treatment group was 6.06%,the total effective rate was 90.91%.The effective rate of control group was 0%,the total effective rate was 81.82%,between the two groups there were no significant difference(P0.05).② The changes of biochemical test between the two groups had no significant difference(P0.05),but for the self-contrast before and after treatment,the RF in both groups had significant difference(P0.01),the CRP in treatment group had significant difference(P0.01),the ESR in both groups had no significant difference(P0.05),the CRP of control group had no significant difference(P0.05).③ Comparaing thesymptom improvement of the two groups after treatment: the pain degree,tenderness level,morning stiffness time of self-contrast in each group had no significant difference before and after treatment(P0.05),the improvement of morning stiffness and joint flexion and extension dysfunction had significant difference(P0.05).The swelling degree,swelling number and tenderness number improvement in treatment group were more than that of control group(P0.01).④Aoqirinailega had no significant adverse reactions on human blood,liver and kidney function.Conclusion: Mongolian medicine Aoqirinailega has an effect in treatment of rheumatoid arthritis,the total effective rate of the two groups are similar,but for treatment of morning stiffness,joint flexion and extension dysfunction,swelling degree,swelling number and tenderness number,Mongolian Aoqirinailega + MTX group is better than than the MTX group.