2010Chinese Journal of Modern Drug ApplicationRequires access

Clinical Analysis of Trimetazidine in patients with stable angina pectoris

Zhou Guang-ron

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Abstract

Objective To study therapeutic effects of Trimetazidine for patients with stable angina pectofs.Methods 82 cases sufferea from stable exertional angina were selected,who were randomly divided into TMZ and control group,in the TMZ group(41 patients) were given TMZ 20 mg three times daily was combined with Betaloe、Bokey、long acting nitrates、Simvastatin.while in the control group(41 patients) were given Betaloc,Bokey,long acting nitrates,Simvastatin.The total period treatment were 12 weeks The change ofAnginal at tacks,exercise duration,heart function,blood pressure,heart rate,ECG were observed in two groups During the period of treatment.Results The change of patients'Anginal attacks,exercise duration,heart function,ECG in Trimetazidine group was significantly higher than that in control group(P 0.05).Conclusion TMZ 20 mg three times daily in combination with existing therapy in stable angina pectoris is very effect.

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What this paper is about

Objective To study therapeutic effects of Trimetazidine for patients with stable angina pectofs.Methods 82 cases sufferea from stable exertional angina were selected,who were randomly divided into TMZ and control group,in the TMZ group(41 patients) were given TMZ 20 mg three times daily was combined with Betaloe、Bokey、long acting nitrates、Simvastatin.while in the control group(41 patients) were given Betaloc,Bokey,long acting nitrates,Simvastatin.The total period treatment were 12 weeks The change ofAnginal at tacks,exercise duration,heart function,blood pressure,heart rate,ECG were observed in two groups During the period of treatment.Results The change of patients'Anginal attacks,exercise duration,heart function,ECG in Trimetazidine group was significantly higher than that in control group(P 0.05).Conclusion TMZ 20 mg three times daily in combination with existing therapy in stable angina pectoris is very effect.

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Available abstract

Objective To study therapeutic effects of Trimetazidine for patients with stable angina pectofs.Methods 82 cases sufferea from stable exertional angina were selected,who were randomly divided into TMZ and control group,in the TMZ group(41 patients) were given TMZ 20 mg three times daily was combined with Betaloe、Bokey、long acting nitrates、Simvastatin.while in the control group(41 patients) were given Betaloc,Bokey,long acting nitrates,Simvastatin.The total period treatment were 12 weeks The change ofAnginal at tacks,exercise duration,heart function,blood pressure,heart rate,ECG were observed in two groups During the period of treatment.Results The change of patients'Anginal attacks,exercise duration,heart function,ECG in Trimetazidine group was significantly higher than that in control group(P 0.05).Conclusion TMZ 20 mg three times daily in combination with existing therapy in stable angina pectoris is very effect.

Key concepts: Trimetazidine, Medicine, Simvastatin, Cardiology, Internal medicine, Angina, Stable angina, Heart rate

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