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2010•Chinese Journal of Modern Drug ApplicationRequires access

Effect of esmolol on the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease

Zhang Jiang-feng

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Abstract

Objective To investigate the effect of esmolol on the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease. Methods 76 patients underwent anesthesia between February,2008 to June,2010 were involved in this research. These patients were divided into 2 groups randomly. The experimental group received esmolol 5 minutes before tracheal intubation. The systemic and pulmonary hemodynamic were monitored. Results The MAP,HP of control group were significantly higher than experimental group. There were 3 patients had ventricular arrhythmias in control group, but no one had ventricular arrhythmias in experimental group. Conclusion Esmolol has a very considerable effect to reduce the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease.

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What this paper is about

Objective To investigate the effect of esmolol on the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease. Methods 76 patients underwent anesthesia between February,2008 to June,2010 were involved in this research. These patients were divided into 2 groups randomly. The experimental group received esmolol 5 minutes before tracheal intubation. The systemic and pulmonary hemodynamic were monitored. Results The MAP,HP of control group were significantly higher than experimental group. There were 3 patients had ventricular arrhythmias in control group, but no one had ventricular arrhythmias in experimental group. Conclusion Esmolol has a very considerable effect to reduce the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease.

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Available abstract

Objective To investigate the effect of esmolol on the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease. Methods 76 patients underwent anesthesia between February,2008 to June,2010 were involved in this research. These patients were divided into 2 groups randomly. The experimental group received esmolol 5 minutes before tracheal intubation. The systemic and pulmonary hemodynamic were monitored. Results The MAP,HP of control group were significantly higher than experimental group. There were 3 patients had ventricular arrhythmias in control group, but no one had ventricular arrhythmias in experimental group. Conclusion Esmolol has a very considerable effect to reduce the hemodynamics response to tracheal intubation in patients with hypertension and coronary heart disease.

Key concepts: Esmolol, Medicine, Tracheal intubation, Hemodynamics, Intubation, Anesthesia, Haemodynamic response, Cardiology

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