Comparative Analysis of Results with Different Automatic Blood Coagulation Analyzers

Objective:The purpose of our study was to analyze results comparability with different automatic blood coagulation analyzers and to estimate clinical acceptability in order to standardize the results with different automatic blood coagulation analyzers.Methods:The values of PT,INR,APTT,FIB and TT were obtained and compared in fresh blood samples and quality controls with instrument matching definite values with SYSMEX CA-1500 and CA-7000 analyzers for 30 days continuously.Results:The coefficient of variations of values of PT,INR,APTT,FIB and TT in inter-day quality controls with SYSMEX CA-1500 and CA-7000 were all less than 5%.Statistical analysis on values of PT,INR,APTT,FIB and TT in fresh blood samples with CA-1500 and CA-7000 analyzers indicated that the p values of t tests were more than 5% and correlation coefficients were between 0.993 and 0.999.The deviations of two instrument were accepted within quality range of USA deviation CLIA 1/2'88 ability requirements.Conclusions:The detected values of PT,INR,APTT,FIB and TT with the two analyzers had close correlation and there was not statistically significantly different.The comparative study on different blood coagulation analyzers was helpful for not only timely finding systematic error,but also ensuring good consistency of detected values in order to provide clinic accurate and consistent detected results and unified evaluation standard of disease diagnosis and observation of curative effect.