A Prospective case-control study of pregnant outcomes in women with abnormal gestational glucose tolerances

Objective:To investigate pregnant outcomes in women with GDM GIGT.Methods:A prospective case-control study was performed in 118 women with abnormal gestational glucose toleraance and 120 cases of normal oral glucose tolerance test(OGTT) as control recruited from Jun 2005 to Aug 2007 in Taiyuan Maternal and Infant Health Care Hospital in order to compare the complications of pregnant women and infants between study and control groups.Results:Average age of women,Pre-pregnancy body mass index,gestational weight getting were significantly higher in GDM/GIGT group than those of control group(P0.05).Age≥30,a family history of diabetes mellitus,a history of bad pregnant outcome,PCOS were significantly higher in GDM/GIGT group than those of control group(P0.05).The rate of macrosomia,cesarean section and neonatal hyperbilirubinemia in GDM/GIGT group was significantly higher than those in control group.The severe complications of infants and women with abnormal geststional glucose tolerances resulted from non-diagnose to GDM/GIGT before delivery.Conclusion:Abnormal gestational glucose tolerances affected the complications of maternal and fetal outcomes,which can be decereased by strict diagnosis and regular management.