Interference of tonifying qi, activating blood and dispersing accumulation on pulmonary fibrosis and the mechanism research

[Objective] To explore the intervention effect of tonifying Qi, activating blood and dispersing accumulation method on pulmonary fibrosis and analyze its mechanism. [Methods] A systematic clinical observation and animal experimental study on the effect of tonifying Qi, activating blood and dispersing accumulation on pulmonary fibrosis and their mechanism research were carried out. [Results] The method of tonifying Qi, activating blood and dispersing accumulation could not only improve the patients' symptoms obviously, but also inhibit the inflammation in lung alveoli, reduce TGF-β1 over-expression. [Conclusion] The method of tonifying Qi, activating blood and dispersing accumulation can improve the patients' symptoms, and play an important role in preventing and curing pulmonary fibrosis.