Influence of Astragalus Anti-Chih Tang on serum IgE,IL-4,IL-12 in patients with allergic rhinitis

Objective To investigate the influence of Astragalus Anti-Chih Tang in patients with allergic rhinitisin.Methods Sixty-eight patients with allergic rhinitis were randomly divided into control group(n=34) and treatment group(n=34).The control group received budesonide,montelukast,and ketotifen.Based on the therapy of the control group,the treatment group received self-prescribed treatment.The serum levels of IgE,IL-4 and IL-12,allergic rhinitis symptom score and airway reactivity were observed before and after treatment.Results After treatment,the serum IgE,IL-4 levels in two groups were significantly lower(P0.05).IL-12 level was significantly higher(P0.05).IL-4 level in the treatment group was significantly lower than that in the control group(P0.05),and IL-12 level was significantly higher than that in the control group(P0.05).After treatment,the allergic rhinitis symptoms score in the treatment group was significantly lower than that in the control group(P0.05).The Fres,R5 and R20 in the treatment group were significantly lower(P0.05) and the treatment group decreased more significantly than the control group(P0.05).Conclusion Astragalus Anti-Chih Tang has reliable efficacy in the treatment of allergic rhinitis.Its therapeutic effect may be related to Th1/Th2 which corrects the balance of the patient's body.