Retrospective analysis of urogenital mycoplasma infection and drug susceptibility results during 2009～2011

Objective To understand the mycoplasma infection in the urogenital tract and the sensitivity of different antibiotics.Methods The culture,identification and susceptibility integration kit was used for testing the urogenital tract secretions from 26 060 cases of suspected urogenital tract infection.Results Mycoplasma infections were detected in 10 481 cases,the positive rate was 40.22%,including Ureaplasma urealyticum(Uu) infection in 9 366 cases(89.36%),Mycoplasma hominis(Mh) infection in 109 cases(l.04%),Uu and Mh mixed infection in 1 006 cases(9.60%).The results of drug susceptibility test showed:Uu infection,Uu and Mh mixed infection were all sensitive to josamycin,doxycycline and minocycline.The resistance rates of guinolones and macrolides were declining. Uu and Mh mixed infection showed broader resistance spectrum and higher resistance rate.Conclusion Uu is the major mycoplasma for urinary tract infection,Uu and Mh mixed infection will increase drug resistance.Josamycin, doxycycline and minocycline can be the preferred choices for treatment of mycoplasma infection.