The clinical significance of high-sensitivity C-reactive protein and S100B protein concentrationsin patients with acute cerebral infarction

Objective To explore the different levels of serum S100B protein in patients with cerebral infarction and highsensitivity C-reactive protein(hs-CRP) concentration and its relationship between the volume of cerebral infarction.Methods Electrochemiluminescence transmission and immune turbidimetry of 56 cases of cerebral infarction patients with serum S100B protein and determination of hs-CRP,and analysis of both the volume and relevance of cerebral infarction.Results The serum S100B protein in patients with cerebral infarction and hs-CRP protein was significantly higher than the normal control group(P0.01),concentration and infarct size and clinical prognosis in a significant correlation.Conclusion S100B protein is a glial marker proteins,as early diagnosis of cerebral infarction sensitive biological indicators of cerebral infarction patients to determine the severity of the lesion, the size of infarct volume have better clinical significance.hs-CRP is a typical acute phase protein,CRP-induced Synthesis and inflammatory cytokines are closely related,the higher the level of inflammatory response is an important biochemical indicators. Combined detection of serum S100B and hs-CRP for patients to judge the severity of cerebral infarct volume and clinical significance of a certain extent.