Detection of Viral Etiology of Children with Acute Respiratory Infection in Wenzhou Area from 2005 to 2006

Objective To investigate the 7 kinds of respirovirus etiology of children with acute respiratory infection(ARI) in Wenzhou area from 2005 to 2006.Methods Three thousand nine hundred and seventy children with ARI visited the Yuying children's hospital were chosen,including 308 children with acute upper respiratory infection(URI) and 3 662 children with lower respiratory infection(LRI).Direct immunofluorescence(DIF) was used to detect the respiratory syncytial virus(RSV),adenovirus(ADV),influenza virus(IV) A and B,parainf-luenza virus(PIV) type 1,2,3 from nasopharyngeal secretions(NPS) collected from these patients.Results Among the 3 970 samples,1 773(44.7%) positive results were determined and the positive rate of RSV(36.2%) was the highest.The isolating rate of respirovirus were all conspicuous difference in sex(χ2=9.2 P0.01),age groups(χ2=120.5 P0.01),difference disease(χ2=101.3 P0.01) and between inpatient and outpatient(χ2=180.4 P0.01).Conclusions RSV is still the leading cause of ARI in infants and young children during winter and spring in Wenzhou from 2005 to 2006.Male patients are easy infected by respirovirus than female patients and the infants(especially less than 6 months) is the same condition than other group.The isolating rate of children with bronchiolitis is highest in all patients,and it is higher in inpatient than that of outpatient.