Viral etiology of hospitalized children with acute respiratory tract infection

Objective:To investigate the viral etiology of acute respiratory tract infection(ARI) of hospitalized children in Yancheng of Jiangsu province so as to provide experimental evidence for children with ARI in the area.Methods:The nasopharyngeal aspirate samples from June 2011 to July 2012 were obtained from 1 582 hospitalized children with ARI.Respiratory syncytial virus(RSV),influenza A(IVA),influenza virus B(IVB),parainfluenza virus 1-3(PIV1-3) and adenovirus were detected by direct immunofluorescence.Results:Four hundred and twenty six case were shown to be infected by respiratory virus in 1582 pediatrics patients and the positive rate was 26.9%.RSV were most frequent(18.3%),followed by adenovirus(2.9%).The overall detection rate of the virus showed significant differences in different age group and seasonal distribution.The highest detection rate of respiratory virus was among children aged 6 month to 1 year and the incidence was higher in winter and spring than in other seasons.Conclusion:RSV and adenovirus was the predominant pathogens of ARI of hospitalized children in Yancheng and the positive rate was significantly associated with age and seasonal distribution.