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2014•Guiding Journal of Traditional Chinese Medicine and PharmacyRequires access

Effect of Mussaenoside on Lipopolysaccharide-induced Nitric Oxide Releasing in RAW 264.7 Cells

Limin Pan

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Abstract

Objective: To study the effect of Mussaenoside on lipopolysaccharide-induced nitric oxide releasing in RAW 264.7 cells. Methods: The cell pattern with RAW264.7 cells activated by lipopolysaccharides(LPS) was established, and the production of NO was examined by NO detection kit. Results: Mussaenoside can obviously reduce the production and release of NO in RAW 264.7 cells, induced by LPS, with statistical difference(P 0.01), comparing with control group. Conclusion: Mussaenoside maybe present an anti-inflammatory effect by reducing NO production.

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What this paper is about

Objective: To study the effect of Mussaenoside on lipopolysaccharide-induced nitric oxide releasing in RAW 264.7 cells. Methods: The cell pattern with RAW264.7 cells activated by lipopolysaccharides(LPS) was established, and the production of NO was examined by NO detection kit. Results: Mussaenoside can obviously reduce the production and release of NO in RAW 264.7 cells, induced by LPS, with statistical difference(P 0.01), comparing with control group. Conclusion: Mussaenoside maybe present an anti-inflammatory effect by reducing NO production.

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Available abstract

Objective: To study the effect of Mussaenoside on lipopolysaccharide-induced nitric oxide releasing in RAW 264.7 cells. Methods: The cell pattern with RAW264.7 cells activated by lipopolysaccharides(LPS) was established, and the production of NO was examined by NO detection kit. Results: Mussaenoside can obviously reduce the production and release of NO in RAW 264.7 cells, induced by LPS, with statistical difference(P 0.01), comparing with control group. Conclusion: Mussaenoside maybe present an anti-inflammatory effect by reducing NO production.

Key concepts: Nitric oxide, Lipopolysaccharide, Chemistry, Raw material, Significant difference, Pharmacology, Medicine, Internal medicine

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Effect of Mussaenoside on Lipopolysaccharide-induced Nitric Oxide Releasing in RAW 264.7 Cells — Research Paper | ScholarLens