Analysis of radiotherapy results and prognostic factors of the adolescence with nasopharyngeal carcinoma

Objective:To analyze the radiotherapy results and prognostic factors of the adolescent with nasopharyngeal carcinoma (NPC) retrospectively.Methods:From Jan 1990 to Dec 1997,49 patients under 30 years old with NPC were treated in our department,which included 31 males and 18 females with the median age of 23.2 (range between 5 and 30) years.All patients were treated with conventional radiotherapy.Total dose delivered to the primary tumor and metastatic cervical lymph nodes was 44～70 Gy in 5～8 weeks.The dose of normal neck ares was 30～44 Gy in 3～5 weeks.Re- sults:With a median follow-up of 84 (14～152) months,the overall 5-year survival rate was 59.2%.The 5-year survival rates of patients with T_(1-2) and T_(3-4) were 74.1% and 40.9% (P＜0.025).The 5-year survival rates of patients with N_(0-1) and N_(2-3) were 81.3% and 48.5% (P＜0.05).Conclusion:The radiotherapy can achieve good results in adolescent NPC patients.T and N Stage are important prognostic factors.