Diagnosis and treatment of xanthogranulomatous pyelonephritis

Objective To explore the diagnosis and treatment of xanthogranulomatous pyelonephritis(XGP).Methods Data of 10 cases of XGP treated in our hospital during 2002 to 2010 were retrospectively studied.The clinical features,laboratory data,imaging findings,diagnosis and differential diagnosis were discussed.Results 9 patients with XGP were misdiagnosed preoperatively,and 1 case was confirmed with combined use of ultrasonography and kidney puncture biopsy.3 cases received radical nephrectomy,4 nephrectomy and 2 partial nephrectomy.1 case was treated with antibiotics.Conclusions XGP doesn't have typical clinical manifestations,which can lead to misdiagnosis.Ultrasonography combined with kidney puncture biopsy is a good method to make a definite diagnosis.Antibiotics and surgery are important therapeutic methods.