2005•Journal of Instrumental AnalysisRequires access

Determination of Borneol and Muscone in Tongshuanxingnao Injections with Solid-phase Extraction and GC-MS

Shouyao Zhang

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Abstract

An assay methods for measuring borneol and muscone in Tongshuanxingnao injections was estabˉlished.Borneol and muscone were extracted with a solid-phase extraction procedure and were simultaneously measured with GC-MS method after a solid-phase extraction procedure.The recoveries and relative standard deviation were97.8%~104.8%and2.72%for borneol and97.6%~105.4%and3.86%for muscone,respectively.The method was simple and accurate and can be used for the quality control of Tongshuanxingˉnao injections.

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What this paper is about

An assay methods for measuring borneol and muscone in Tongshuanxingnao injections was estabˉlished.Borneol and muscone were extracted with a solid-phase extraction procedure and were simultaneously measured with GC-MS method after a solid-phase extraction procedure.The recoveries and relative standard deviation were97.8%~104.8%and2.72%for borneol and97.6%~105.4%and3.86%for muscone,respectively.The method was simple and accurate and can be used for the quality control of Tongshuanxingˉnao injections.

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Available abstract

An assay methods for measuring borneol and muscone in Tongshuanxingnao injections was estabˉlished.Borneol and muscone were extracted with a solid-phase extraction procedure and were simultaneously measured with GC-MS method after a solid-phase extraction procedure.The recoveries and relative standard deviation were97.8%~104.8%and2.72%for borneol and97.6%~105.4%and3.86%for muscone,respectively.The method was simple and accurate and can be used for the quality control of Tongshuanxingˉnao injections.

Key concepts: Borneol, Chemistry, Chromatography, Extraction (chemistry), Solid phase extraction, Gas chromatography–mass spectrometry, Relative standard deviation, Detection limit

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