Clinical Study of Butylphtalide Soft Capsules Combined with Ginkgo Leaf Extract and Dipyridamole Injection for Acute Cerebral Infarction

Objective:To evaluate the clinical efficacy and safty of combined use of butylphtalide soft capsules and ginkgo leaf extract and dipyridamole injection in the treatment of acute cerebral infarction.Methods:72 cases of acute cerebral infarction were randomly divided into A,B,C groups,on the basis of routine treatment,A group was given butylphthalide soft capsules orally and ginkgo leaf extract and ginkgo leaf extract and dipyridamole injection infusion, B group was given ginkgo leaf extract and dipyridamole injection infusion,treatment,using of the same,C group was given runtine treatment,three groups were treated for 14 days.In the end before starting treatment,after treatment,clinical neural function defect score(NIHSS) and activities of daily living scale (BI) score,observed and compared the treatment effect,and to evaluate the adverse effects.Results:A,B,C groups after treatment,NIHSS and BI scores were significantly lower than that before treatment( P 0.05),after treatment in A group,NIHSS and BI were significantly lower in B and C groupss ( P 0.05).In A group, the treatment efficiency(87.50%) was significantly higher than that of B group(75.00%),there was significant difference ( P 0.05).Conclusion:The combined application of butylphthalide and ginkgo leaf extract and dipyridamole injection on acute cerebral infarction onset synergistic therapeutic effect with a certain degree of patients,but the clinical application is safe.