Experimental study of the therapeutic effect of Longbikang on benignprostatic hyperplasia

Objective To observe the therapeutic effect of Longbikang on benign prostatic hyperplasia.Methods Male SD rats were divided into control group, model group, Qianliekang group, low-dose Longbikang group,middle-dose Longbikang group and high-dose Longbikang group.The both of didymus of rats were removed and testosterone propionate was injected to make model of rat benign prostatic hyperplasia.Prostate humid weight, prostate index and prostate pathological changes were observed.Results Prostate humid weight and prostate index in model group were significantly increased,as compared with those in control group(P0.01).These parameters in Longbikang groups and Qianliekang group were significantly decreased,as compared with those in model group%(P0.01),and these parameters in high-dose Longbikang group were the lowest in Longbikang groups and QianlieKang group.The light microscope showed that the pathological structure in high-dose Longbikang group was similar to that of control group.Conclusion Longbikang has the effect of inhibiting prostatic hyperplasia,and the therapeutic effect is positively correlated with the dosage.