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Clinical study of treating skin pruritus caused by uremia by hemoperfusion combined with hemodialysis

Xie Quan-kun

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Abstract

Objective:To study the effect of hemoperfusion(HP) combined with hemodialysis(HD) on the patients with uremia. Methods:24 maintenance hemodialysis patients were randomly divided into the test group(n=12) and control group(n=12). The hemoperfusion connected with hemodialysis in series was used in the test group and the hemodialysis in the control group. Anticoagulant is heparin. The hemodialysis blood flow rate was 200~250 ml/min, dialysate flow rate was 500ml/min. The time of pruritus relief and the level of SCr、BUN、PTH、β2-MG in the blood were measured before and after treatment. Results:The relief of skin itching and the clearance of PTH and β2-MG were significantly higher in the test group than the control group(P0.05).Conclusion: The treatment of hemoperfusion connected with hemodialysis in series can effectively relieve skin pruritus and clean the middle-large molecular substance.

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What this paper is about

Objective:To study the effect of hemoperfusion(HP) combined with hemodialysis(HD) on the patients with uremia. Methods:24 maintenance hemodialysis patients were randomly divided into the test group(n=12) and control group(n=12). The hemoperfusion connected with hemodialysis in series was used in the test group and the hemodialysis in the control group. Anticoagulant is heparin. The hemodialysis blood flow rate was 200~250 ml/min, dialysate flow rate was 500ml/min. The time of pruritus relief and the level of SCr、BUN、PTH、β2-MG in the blood were measured before and after treatment. Results:The relief of skin itching and the clearance of PTH and β2-MG were significantly higher in the test group than the control group(P0.05).Conclusion: The treatment of hemoperfusion connected with hemodialysis in series can effectively relieve skin pruritus and clean the middle-large molecular substance.

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Available abstract

Objective:To study the effect of hemoperfusion(HP) combined with hemodialysis(HD) on the patients with uremia. Methods:24 maintenance hemodialysis patients were randomly divided into the test group(n=12) and control group(n=12). The hemoperfusion connected with hemodialysis in series was used in the test group and the hemodialysis in the control group. Anticoagulant is heparin. The hemodialysis blood flow rate was 200~250 ml/min, dialysate flow rate was 500ml/min. The time of pruritus relief and the level of SCr、BUN、PTH、β2-MG in the blood were measured before and after treatment. Results:The relief of skin itching and the clearance of PTH and β2-MG were significantly higher in the test group than the control group(P0.05).Conclusion: The treatment of hemoperfusion connected with hemodialysis in series can effectively relieve skin pruritus and clean the middle-large molecular substance.

Key concepts: Hemoperfusion, Medicine, Hemodialysis, Uremia, Itching, Anesthesia, Surgery, Blood flow

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Clinical study of treating skin pruritus caused by uremia by hemoperfusion combined with hemodialysis — Research Paper | ScholarLens