Clinical investigation of gastric epithelial dysplasia and intestinal metaplasia in Western Yu Region,China

Objective:To explore the clinical epidemiologic characteristics and tendency of gastric epithelial dysplasia and intestinal metaplasia in Western Yu region.Methods:The clinical data of 21932 patients by gastroscopy were collected from 2007 to 2010,the clinical and pathology data of gastric epithelial dysplasia and intestinal metaplasia were analyzed retrospectively.Results:Age,at which dysplasia and dysplasia accompanied with intestinal metaplasia could be deteced,showed an increasing trend.The degree of dysplasia was related to age.The percentage of patients who were above 60 years of age in severe dysplasia was much higer than that in mild and moderate dysplasia(P0.05),and in moderate dysplasia was much higher than mild dysplasia(P0.05).The proportion of patients who were above 60 years of age was significantly greater in moderate intestinal metaplasia compared with that in mild intestinal metaplasia.The proporation of patients who were above 60 years of age was significantly higher in the gastric cardia than that in gastric corpus and gastric incisura.The detection of Hp in gastric epithelial dysplasia and intestinal metaplasia was higher than in chronic superficial gastritis.Conclusion:Gastric epithelial dysplasia and intestinal metaplasia was related with age and Helicobacter pylori and it mostly located on the gastric cardia.