Analysis of the Endoscopic and Pathologic Characteristics of Intestinal Metaplasia and Intestinal Type Gastric Cancer

] Objective To explore the relation between intestinal metaplasia and intestinal type gastric cancer, and the impact factors of intestinal metaplasia, by making a retrospective analysis on the patients with intestinal metaplasia and intestinal type gastric cancer. Methods Totally 14 766 person times, examined by gastroscope from 1998 to 2003, were selected as the cases for the statistical analysis. Results The age, at which moderate, severe degree intestinal metaplasia and intestinal type gastric cancer could be detected, showed an increasing trend, and there were significant differences among the age groups (P0.01). The detected age of the intestinal type gastric cancer was lowest at the gastric incisura, which was significantly different from other parts (P0.01), and the detected age at gastric antrum, corpus, fundus and cardia cancer were not significantly different from one another. The detective rate of the intestinal type gastric cancer in male and female was 3.44% and 1.18% respectively which had significant difference (P0.01), and the detected rate of moderate, severe degree intestinal metaplasia was 5.46% and 5.17%, respectively, which had no significant difference (P0.05). The Hp positive rate of gastric antrum with moderate, severe degree intestinal metaplasia (37.44% and 35.80%, respectively) was higher than that with no or only slight intestinal metaplasia (30.19%). The degree of intestinal metaplasia was related to the gastric mucous atrophy. Conclusions Intestinal metaplasia takes place at earlier ages than intestinal type gastric cancer and the both had a different distribution in the sexes. The moderate, severe degree intestinal metaplasia is related to the Hp infection and its degree is related to the gastric mucous atrophy.