Analysis of the combined treatment of TURP and TUVP on severe benign prostatic hyperplasia in 256 cases

Objective To evaluate the safety and efficacy of transurethral resection of prostate(TURP) combined with transurethral electrovaporization of the prostate(TUVP) for the treatment of patients with severe benign prostatic hyperplasia(BPH).Methods 256 cases of severe BPH underwent TURP combined with TUVP therapy between April 2004 and January 2011 were included in this retrospective analysis.The results of international prostate symptom score(IPSS),quality of life score(QOL),maximum flow rate(Qmax) and residual urine volume(RUV) before and after treatment were compared.Results The mean time of the surgery was 78 min(range 58 to 115 min).No severe complication such as massive hemorrhage,transurethral resection syndrome(TURS)and urinary incontinence was observed.During 6-24 months follow-up after operation,IPSS,QOL and RUV scores were significantly decreased from 31.2± 3.8 to 6.3± 1.2,from 5.2±0.8 to 2.0±0.4 and from 216.6±53.5 to 16.1±8.6 respectively.Qmax was increased from(3.5±1.2)mL/s to(16.5±3.0)mL/s.The changes of IPSS,QOL,RUV scores and Qmax between the preoperative and postoperative were significantly different(P0.05).Conclusion The combined use of TURP and TUVP is safe and effective in the treatment of severe BPH.