Appliccation of Hs-CRP and WBC combined detection in children with respiratory tract infections

Objective To explore the application value of joint detection of whole-blood high-sensitivity C-reactive protein (hs-CRP) and white blood cell count (WBC) in children with acute respiratory infections.Methods To select 350 cases of acute upper respiratory tract infection in our hospital,including 50 neonats,100 infants as well as 200 children,30 pupils as the control group. hs-CRP in peripheral blood was detected and the routine blood test was performed. 40 cases in each of bacterial,mycoplasma and viral infections were selected from the infantile and children groups and copmared with the control group.Results In neonatal group,the hs-CRP positive rate was 38%,WBC positive rate was only 1%; in infantile group,the hs-CRP positive rate was 44%,the WBC positive rate was 13%; in children group,the hs-CRP was 61%,the WBC positive rate was 41%. In viral infection,hs-CRP and WBC had statistical difference compared with the control group,(P0.05); mycoplasma and bacterial groups had statistical difference compared with the control group (P0.01),and the bacterial group was higher than mycoplasma group with the statistical difference (P0.01).Conclusion Combined detection of hs-CRP and WBC has great value in differentiating upper respiratory tract infections in children.