Clinical observation of inhalation therapy of salmeterol/fluticasone for stable chronic obstructive pulmonary disease

Objective:To investigate the therapeutic effect of inhaled long-acting β2-agonists and pre-mixed corticosteroids of salmeterol /fluticasone propionate on stable chronic obstructive pulmonary disease(COPD) patients.Methods:120 patients diagnosed as stable COPD were randomly divided into two groups,both were taken combined treatment.The treatment group(n = 60) was treated with salmeterol /fluticasone propionate powder inhalation(50 μg/250 μg),2 times·d-1 beside combined therapy;the control group(n = 60) was treated with beclomethasone dipropionate inhalation.Treat for 3 months,evaluate the changes of lung function and SGRQ survey score before and after treatment.Results:Integration of clinical symptoms and lung function indexes of the two groups were both improved;the treatment group was significantly better than the control group(P 0.05).Conclusion:Inhaled salmeterol /fluticasone propionate dry powder can improve lung function and life quality of stable COPD patients.