THE EXPERIMENTAL STUDY ON THE RADIOFREQUENCY ABLATION THERAPY OF THE RABBIT LIVER CARCINOMA

Objective To explor the therapeutic effects and significances of radiofrequency ablation(RFA) of the hepatic neoplasm.Methods The hepatic neoplasm animal model was established by injecting the VX2 tumor constitution mass into the liver of the rabbits in surgery.The animal models were randomly divided into two groups: the experimental group which were treated by RFA therapy and the control group.And then the changes of hepatic function,hepatic neoplasm ultrasonography were observed respectively.Results Hepatic function changed apparently in 1 week and restored gradually to the normal level in 2 week(P0.05).The volume of neoplasm changed little in 1 week after RFA and then size-downed gradually.The blood stream signals of hepatic neoplasm after RFA therapy decreased apparently or disappeared.Conclusion The therapeutic effect of RFA on the hepatic neoplasm is positive.RFA therapy can result in hepatic function lesion.Important technic support was supplied by ultrasound for clinical RFA therapy.