Clinical analysis on 8 cases of leukemia complication pregnancy

Objective To explore the rational treatment program of leukemia complicating pregnancy. Method We carried out a retrospective study on 8 cases ofleukemia complicating pregnancy and treated with chemotherapy from June 1998 to June 2008 in the first hospi- tal of Jilin university. Results Review of the cases receiving chemotherapy revealed no harm to the children in cases of the onset and poor prognosis for the children in cases of early onset. However,the overall results seemed to indicate that the earlier the chemotherapy was instituted,the better the outcome will be for the mothers. Conclusion A protocol is thus proposed with emphasis on the timing of institution of chemotherapy in relation to the course of pregnancy. Briefly,induced abortion followed by combined chemotherapy in early pregnancy and timely combined chemotherapy in midand late pregnancy are recommended. Brief cessation of chemotherapy during parturition may be necessary and sufficient supportive measures are needed.