ScholarLens Back to search
2011•Zhongguo yaofangRequires access

Content Determination of Borneol and Isoborneol in Huzhang Cream by GC-MS

YI Xue-dong

Open publisher page 0 citations

Abstract

OBJECTIVE:To establish a method for the content determination of borneol and isoborneol in Huzhang cream.METHODS:GC-MS method was adopted.The Agilent HP-5MS chromatographic column was used with programmed temperature,high purity He as carrier gas and the vaporizer temperature at 260℃.The flow rate was 1 mL·min-1,the sample size was 2 μL amd split ratio 20:1.The ion source temperature was 230℃ and quadropole temperature was 150℃.Ionization mode was EI.RESULTS:The isoborneol and borneol both showed a good linear relationship were at the range of 0.005～0.061 μg and 0.012～0.150 μg,respectively(r=0.999 7).The average recoveries were 99.56%(RSD=2.20%,n=6)and 99.79%(RSD=2.03%,n=6),respectively.CONCLUSION:The method is stable,simple,sensitive and rapid.It can be used for the content determination of isoborneol and borneol in Huzhang cream.

About this research paper

What this paper is about

OBJECTIVE:To establish a method for the content determination of borneol and isoborneol in Huzhang cream.METHODS:GC-MS method was adopted.The Agilent HP-5MS chromatographic column was used with programmed temperature,high purity He as carrier gas and the vaporizer temperature at 260℃.The flow rate was 1 mL·min-1,the sample size was 2 μL amd split ratio 20:1.The ion source temperature was 230℃ and quadropole temperature was 150℃.Ionization mode was EI.RESULTS:The isoborneol and borneol both showed a good linear relationship were at the range of 0.005～0.061 μg and 0.012～0.150 μg,respectively(r=0.999 7).The average recoveries were 99.56%(RSD=2.20%,n=6)and 99.79%(RSD=2.03%,n=6),respectively.CONCLUSION:The method is stable,simple,sensitive and rapid.It can be used for the content determination of isoborneol and borneol in Huzhang cream.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE:To establish a method for the content determination of borneol and isoborneol in Huzhang cream.METHODS:GC-MS method was adopted.The Agilent HP-5MS chromatographic column was used with programmed temperature,high purity He as carrier gas and the vaporizer temperature at 260℃.The flow rate was 1 mL·min-1,the sample size was 2 μL amd split ratio 20:1.The ion source temperature was 230℃ and quadropole temperature was 150℃.Ionization mode was EI.RESULTS:The isoborneol and borneol both showed a good linear relationship were at the range of 0.005～0.061 μg and 0.012～0.150 μg,respectively(r=0.999 7).The average recoveries were 99.56%(RSD=2.20%,n=6)and 99.79%(RSD=2.03%,n=6),respectively.CONCLUSION:The method is stable,simple,sensitive and rapid.It can be used for the content determination of isoborneol and borneol in Huzhang cream.

Key concepts: Borneol, Vaporizer, Chromatography, Content determination, Chemistry, Linear range, Analytical Chemistry (journal), Detection limit

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Content Determination of Borneol and Isoborneol in Huzhang Cream by GC-MS — Research Paper | ScholarLens