Antibiotic resistance and minimum inhibitory concentration distribution of Stenotrophomonas maltophilia

Objective To analyze the antibiotic resistance and distribution of minimum inhibitory concentrations (MIC) of S. maltophilia and provide useful reference for rational antibiotic treatment of S. maltophilia infection. Methods MIC of 8 antibiotics against S. maltophilia were determined using two-fold agar dilution method.Results A total of 103 strains of S. maltophilia were multi-drug resistant. The resistance rate of S. maltophilia to trimethoprim-sulfamethoxazole, ticarcillin-clavavulanic acid, ciprofloxacin, levofloxacin and gatifloxacin were lower (34.0%, 16.5%, 26.2%, 5.8% and 4.9% respectively).Conclusions The pathogen should be isolated as early as possible when S. maltophilia infection is suspected. Antibiotic therapy for S. maltophilia infection should be appropriate based on susceptibility testing and MIC results.