Observation on thrombolytic therapy on blood vessel reperfusion by different times after senile patients with AMI

Objective:To study the effect of thrombolytic therapy on blood vessel reperfusion by different times after acute myocardial infarction(AMI).Methods:Eighty-five senile patients with AMI were divided into five groups according to different times after intravenous thrombolytic therapy.They were ≤{2 h},2~{4 h},4~{6 h},6~{12 h} and 12~{24 h} group.Results:Reperfusion rate of the 5 groups were 84.6%、76.9%、68.8%、45.6% and 50% respectively,with significant difference between the former three groups and the latter two groups(P0.05).The mortality rate were 0、2.6%、12.5%、18.2% and 16.7% respectively.The time from the beginning of dissolving to blood vessel reperfusion was positively related with the time from onset of AMI thrombolytic therapy(P0.05).Only 35-80 minutes within 2 hours after onset of AMI,but 90-155 minutes within 6-{12 h}.Conclusions:In the senile patients(over 70 years old),within 6 after onset of AMI,the reperfusion effect of blood vessels was the best.As for the cases within 6-{12 h} after the onset of AMI,the thrombolytic effect were also favourable and reduced the complication.