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Immunohistochemical study of heat shock protein 70 in mouse endometrium during early pregnancy

Shun Zhang

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Abstract

Objective:To study the expression of heat shock protein (HSP) 70 in mouse endometrium during early pregnancy.Methods:Immunohistochemical method was used in the experiment.Results:HSP 70 mainly distributed in stroma cells and decidual cells of endometrium lamina propria and was negative in endometrium epithelium and glandular epithelium.HSP 70 immunoreactivity positive cells in pregnant mouse was strikingly increased compared with control mouse ( P 0.01),and it increased with the increasing of gestation day ages.( P 0.01).Conclusion:HSP 70 participates in proliferation of stroma cells in endometrium decidualization and is closely related to the decidualization..

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What this paper is about

Objective:To study the expression of heat shock protein (HSP) 70 in mouse endometrium during early pregnancy.Methods:Immunohistochemical method was used in the experiment.Results:HSP 70 mainly distributed in stroma cells and decidual cells of endometrium lamina propria and was negative in endometrium epithelium and glandular epithelium.HSP 70 immunoreactivity positive cells in pregnant mouse was strikingly increased compared with control mouse ( P 0.01),and it increased with the increasing of gestation day ages.( P 0.01).Conclusion:HSP 70 participates in proliferation of stroma cells in endometrium decidualization and is closely related to the decidualization..

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Available abstract

Objective:To study the expression of heat shock protein (HSP) 70 in mouse endometrium during early pregnancy.Methods:Immunohistochemical method was used in the experiment.Results:HSP 70 mainly distributed in stroma cells and decidual cells of endometrium lamina propria and was negative in endometrium epithelium and glandular epithelium.HSP 70 immunoreactivity positive cells in pregnant mouse was strikingly increased compared with control mouse ( P 0.01),and it increased with the increasing of gestation day ages.( P 0.01).Conclusion:HSP 70 participates in proliferation of stroma cells in endometrium decidualization and is closely related to the decidualization..

Key concepts: Decidualization, Endometrium, Lamina propria, Immunohistochemistry, Stromal cell, Decidua, Andrology, Stroma

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