The experimental study of nonunion treatment with percutaneous autogenous concentrated bone marrow grafting

Objective To observe the experiental effect of nonunion treatment with percutaneous autogenous concentrated bone marrow grafting. Methods 32 rabbits were used to make nonunion models,they were grouped randomly into two groups(Bone marrow stem cells group,Internal fixationand grafting group). Periodical standardized radiographs,histology and heal rate after 8weeks and 12weeks were perfoermed. Results The gap changes of bone union at 8weeks and 12weeks after treatment in group A and B,were not statically significant. Conclusion Percutaneous autogenous concentrated bone marrow of the rabbits can induce osteogenesis in bone nonunion,its efficacy appears to be related to the concentration of bone marrow stem cells in the graft.