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Effect of Tanreqing Injection on Acute Lung Injury in Patients Undergoing Non-invasive Positive Pressure Ventilation

Zhou Fa-chun

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Abstract

OBJECTIVE:To evaluate the effect of Tanreqing injection on acute lung injury in patients undergoing noninvasive positive pressure ventilation(NIPPV).METHODS: 162 patients with acute lung injury were randomly assigned to receive Tanreqing injection plus NIPPV(treatment group) or NIPPV alone(control group).At 8,24,48 h of undergoing NIPPV,parameters such as patients' subjective symptoms,vital sign,blood gas analysis PaO2/FiO2 and NIPPV duration etc were recorded.RESULTS: In the treatment group compared with the control group,the mean duration of NIPPV was shorter(P 0.05);dyspnea improved more significantly at 8,24,48 hours(P0.05);heart rate improved more significantly at 24 and 48 hours(P0.05);and PaO2/FiO2 increased more significantly at 8,24,48 hours(P0.05).CONCLUSION: Tanreqing can relieve the acute lung injury,prevent which from progressing to acute respiratory distress syndrome(ARDS) and effectively shorten the NIPPV duration.

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What this paper is about

OBJECTIVE:To evaluate the effect of Tanreqing injection on acute lung injury in patients undergoing noninvasive positive pressure ventilation(NIPPV).METHODS: 162 patients with acute lung injury were randomly assigned to receive Tanreqing injection plus NIPPV(treatment group) or NIPPV alone(control group).At 8,24,48 h of undergoing NIPPV,parameters such as patients' subjective symptoms,vital sign,blood gas analysis PaO2/FiO2 and NIPPV duration etc were recorded.RESULTS: In the treatment group compared with the control group,the mean duration of NIPPV was shorter(P 0.05);dyspnea improved more significantly at 8,24,48 hours(P0.05);heart rate improved more significantly at 24 and 48 hours(P0.05);and PaO2/FiO2 increased more significantly at 8,24,48 hours(P0.05).CONCLUSION: Tanreqing can relieve the acute lung injury,prevent which from progressing to acute respiratory distress syndrome(ARDS) and effectively shorten the NIPPV duration.

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Available abstract

OBJECTIVE:To evaluate the effect of Tanreqing injection on acute lung injury in patients undergoing noninvasive positive pressure ventilation(NIPPV).METHODS: 162 patients with acute lung injury were randomly assigned to receive Tanreqing injection plus NIPPV(treatment group) or NIPPV alone(control group).At 8,24,48 h of undergoing NIPPV,parameters such as patients' subjective symptoms,vital sign,blood gas analysis PaO2/FiO2 and NIPPV duration etc were recorded.RESULTS: In the treatment group compared with the control group,the mean duration of NIPPV was shorter(P 0.05);dyspnea improved more significantly at 8,24,48 hours(P0.05);heart rate improved more significantly at 24 and 48 hours(P0.05);and PaO2/FiO2 increased more significantly at 8,24,48 hours(P0.05).CONCLUSION: Tanreqing can relieve the acute lung injury,prevent which from progressing to acute respiratory distress syndrome(ARDS) and effectively shorten the NIPPV duration.

Key concepts: Medicine, ARDS, Anesthesia, Acute respiratory distress, Positive pressure ventilation, Ventilation (architecture), Lung, Internal medicine

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Effect of Tanreqing Injection on Acute Lung Injury in Patients Undergoing Non-invasive Positive Pressure Ventilation — Research Paper | ScholarLens