Effect of different nutrition modes on intracranial infections in severe brain injury patients

OBJECTIVE To study the effects of different nutrition modes on the intracranial infections in severe brain injury patients so as to reduce the incidence of intracranial infections and improve the medical quality. METHODS A total of 100cases of severe craniocerebral injury,who were treated in the hospital from Feb 2011to Jan 2013,were enrolled in the study,then the subjects with the intracranial infections were divided into two groups according to the nutrition mode,the enteral nutrition group was given with the enteral nutrition 48hours after the surgery,while the parenteral nutrition group was treated with the parenteral nutrition,and the incidence of postoperative intracranial infections was observed and compared between the two groups.RESULTS The leukocyte counts,lymphocyte counts,and level of C-reactive protein at 1,4,7,15days after the surgery were significantly higher in the enteral nutrition group than in the parenteral nutrition group,the differences were significant(P0.05).The length of ICU stay was(6.38±5.6)days in the enteral nutrition group,(12.5±8.2)days in the parenteral nutrition group;the duration of use of antibiotic was(7.4±4.3)days in the enteral nutrition group,(13.8±7.9)days in the parenteral nutrition group;the incidence of SIRS was 0 in the enteral nutrition group, 4.0% in the parenteral nutrition group;the GCS score was(12.5±3.3)points in the enteral nutrition group,(9.1±0.4)points in the parenteral nutrition group;the SOFA score was(2.93±2.18)points in the enteral nutrition group,(2.72±4.72)points in the parenteral nutrition group;the APACHEⅡ score was(2.93±2.18) points in the enteral nutrition group,(5.48±5.13)points in the parenteral nutrition group;the mortality was 2.0% in the enteral nutrition group,6.0% in the parenteral nutrition group;the incidence of complications was 4.0% in the enteral nutrition group,18.0% in the parenteral nutrition group;the differences were significant(P 0.05).CONCLUSIONTo perform the standardized enteral nutrition for the severe brain injury patients in early stage may facilitate recovery from the infections and improve the clinical effect.