A Comparison on the expression of NO system between the Blood from Portal Vein and the Blood from Inferior Vena Caval in patients with chronic hepatitis patients and liver cirrhosis patients

Objective: To study the effect of NO in the course in which hyperdynamic circulation with hepatic cirrhosis occurs in patients with chronic hepatitis patients and liver cirrhosis patients.Methods:The plasma NO activity was measured with colorimetric analysis including the group of chronic hepatitis(n=20),the group of liver cirrhosis(n=20) and the group of control(n=10).Results: The plasma iNOS activity in portal venous and peripheral with chronic hepatitis and cirrhosis patients are all increased than it is in control group.Furthermore,the iNOS activity in portal venous was more visible increased.Conclusion:iNOS/NO system has an important effect which maintains the state of diastolic blood vessels on the occurrence and development with hepatic cirrhosis.