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Study on Chemical Constituents of Periploca forrestii Schlecht.

Zhao Yan-tao

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Abstract

OBJECTIVE To study the chemical constituents of Periploca forrestii Schlecht.METHODS Various chromatographic techniques were used to isolate the constituents,and their structures were identified by spectral and chemical methods.RESULTS Thirteen compounds were isolated and identified as β-sitosterol(1),ursolic acid(2),emodin(3),cleomiscosin A(4),cleomiscosin B(5),daucosterol(6),periforosideⅠ(7),periplocin(8),2α,3β,5,24-tetrahydroxy-olean-12-en-28-oic acid(9),questin(10),glycoside E(11),vanillic acid(12),and 3,5-dimethoxy-4-hydroxybenzoic acid(13).CONCLUSION Compounds 4,5,9,12 and 13 are isolated for the first time from P.forrestii Schlecht..

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OBJECTIVE To study the chemical constituents of Periploca forrestii Schlecht.METHODS Various chromatographic techniques were used to isolate the constituents,and their structures were identified by spectral and chemical methods.RESULTS Thirteen compounds were isolated and identified as β-sitosterol(1),ursolic acid(2),emodin(3),cleomiscosin A(4),cleomiscosin B(5),daucosterol(6),periforosideⅠ(7),periplocin(8),2α,3β,5,24-tetrahydroxy-olean-12-en-28-oic acid(9),questin(10),glycoside E(11),vanillic acid(12),and 3,5-dimethoxy-4-hydroxybenzoic acid(13).CONCLUSION Compounds 4,5,9,12 and 13 are isolated for the first time from P.forrestii Schlecht..

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Available abstract

OBJECTIVE To study the chemical constituents of Periploca forrestii Schlecht.METHODS Various chromatographic techniques were used to isolate the constituents,and their structures were identified by spectral and chemical methods.RESULTS Thirteen compounds were isolated and identified as β-sitosterol(1),ursolic acid(2),emodin(3),cleomiscosin A(4),cleomiscosin B(5),daucosterol(6),periforosideⅠ(7),periplocin(8),2α,3β,5,24-tetrahydroxy-olean-12-en-28-oic acid(9),questin(10),glycoside E(11),vanillic acid(12),and 3,5-dimethoxy-4-hydroxybenzoic acid(13).CONCLUSION Compounds 4,5,9,12 and 13 are isolated for the first time from P.forrestii Schlecht..

Key concepts: Daucosterol, Vanillic acid, Ursolic acid, Chemical constituents, Chemistry, Emodin, Chromatography

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